有的玩笑不能再开了，毕竟他们都是大孩子了。 — Chinese Grammar HSK 5 flashcard

Some jokes can no longer be opened, after all they are older children.

yǒude wánxiào bùnéng zài kāi le，bìjìng tāmen dū shì dàháizǐ le 。

Expressing "after all" with "bijing"

毕竟 ⋯⋯ / 虽然 ⋯⋯ ，但 + 毕竟 ⋯⋯ ，(as a result) ⋯⋯